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Icon LabOnAChipWe are pleased to announce a recent publication on our work in Scaffold-Needs:

Crowe, J. A. and El-Tamer, A. and Nagel, D. and Koroleva, A. V. and Madrid-Wolff, J. and Olarte, O. E. and Sokolovsky, S. and Estevez-Priego, E. and Ludl, A.-A. and Soriano, J. and Loza-Alvarez, P. and Chichkov, B. N. and Hill, E. J. and Parri, H. R. and Rafailov, E. U.

Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks

Lab Chip, 2020, Advance Article

▶ https://doi.org/10.1039/C9LC01209E

The paper was published under open access.

 


3D human iPSC-derived neuronal network developed in a laser fabricated scaffold. Green: neurons stained with MAP2 neuronal marker; Blue: DAPI nuclear staining.Laser fabricated scaffolds represent an attractive 3D culture platform for the development of in vitro 3D modelling tools in neuroscience.
The image on the right shows a 3D human iPSC-derived neuronal network developed in a laser fabricated scaffold. Green: neurons stained with MAP2 neuronal marker; Blue: DAPI nuclear staining. 70 days in culture.

▶ Click here to watch the animation!

 


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This project has received funding from the European Union's Horizon 2020
research and innovation programme under grant agreement No 851734

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